| 17.04.2021 | 1 | X | 2 | B's |
|---|
| 18:00 |  Le Mans FC - Avranches | 2.18 | 3.00 | 3.60 | 3 |
| 19:00 |  Concarneau - FC Bastia Borgo | 2.34 | 2.75 | 3.45 | 3 |
| 19:00 |  FC Sete 34 - Stade Lavallois Mayenne FC | 2.45 | 2.65 | 3.05 | 1 |
| 19:00 |  Sete 34 FC - Stade Laval | 2.50 | 2.75 | 3.15 | 1 |
| 20:00 |  FC Villefranche-Beaujolais - Us Creteil Lusitanos | 1.74 | 3.05 | 5.00 | 1 |
| 20:00 |  Red Star FC - SO Cholet | 1.87 | 3.05 | 4.70 | 3 |
| 20:00 |  US Boulogne Cote D Opale - Saint-Brieuc | 2.21 | 2.65 | 4.15 | 3 |
| 20:00 |  Villefranche - US Creteil | 1.74 | 3.15 | 5.20 | 2 |
| 19.04.2021 | 1 | X | 2 | B's |
|---|
| 18:30 |  Bastia SC - Lyon Duchere | 1.58 | 3.50 | 6.20 | 3 |
| 18:30 | US Quevillaise-Rouen Metropole - Annecy FC | 2.14 | 2.85 | 3.80 | 3 |
| 20.04.2021 | 1 | X | 2 | B's |
|---|
| 18:00 | US Boulogne Cote D Opale - Stade Laval | 2.25 | 2.85 | 3.55 | 1 |
| 21.04.2021 | 1 | X | 2 | B's |
|---|
| 19:00 | Orleans US - Le Mans UC 72 | 1.90 | 3.05 | 4.50 | 2 |
French National
Cska Moscow
Rotor Volgograd
Arsenal London
SK Slavia Prague
AC Ajaccio
Valenciennes FC
Jastrzebski Wegiel - ZAKSA Kedzierzyn-Kozle
